This study seeks to investigate the multifaceted impacts of the on-going trade conflict between the United States and China on African economies. It began by outlining the origins of the trade war, which escalated in 2018 due to tariffs imposed by the U.S. on Chinese goods and subsequent retaliatory measures by China. The trade war disrupted global supply chains, altered trade patterns, and influenced investment flows, all of which had significant implications for Africa. The paper highlighted those African nations, heavily reliant on trade with both China and the U.S., faced both opportunities and challenges. On one hand, the trade war created the potential for increased demand for African agricultural products, minerals, and textiles as the U.S. and China sought alternative suppliers. On the other hand, countries dependent on exports to China suffered from reduced demand due to economic slowdowns linked to the trade conflict. Investment dynamics were also affected, with China's Belt and Road Initiative facing re-evaluation amid the trade war, while the U.S. sought to strengthen ties with African nations through initiatives like Prosper Africa. The document discussed the volatility of commodity prices and the need for African countries to diversify their economies to mitigate risks associated with reliance on specific exports. Moreover, the paper emphasized the importance of developing robust manufacturing sectors, enhancing trade partnerships, investing in infrastructure, and leveraging technology and innovation to navigate the challenges posed by the trade war. It concluded by advocating for targeted policy measures aimed at economic diversification, regional integration, and building human capital to foster resilience and sustainable growth in African economies amidst the shifting global trade landscape.