This study examined the impact of the impact of entrepreneurship development on the Performance of Selected SMEs in Abia State. The objectives are to examine the impact of innovation on effectiveness of Selected SMEs in Abia State and determine the relationship between entrepreneurship development on performance of Selected SMEs in Abia State. The research adopted a descriptive survey design. Primary and secondary data was used for the study. The total population of the study was one hundred (100) staff of selected SMEs in Abia State. The sample size of 80 was determined from Taro Yamane formula. The researcher adopted simple random sampling technique. Regression model was adopted to test the hypotheses of the study. The findings of the study showed that Innovation has a significant impact on effectiveness of Selected SMEs in Abia State with p-value = .005 < .05 significant level. There is a positive relationship between entrepreneurship development on Organizational Performance of Selected SMEs in Abia State. The study recommended that Good entrepreneurs should have interest and vision, the skills to start a business and the willingness to invest in many areas of the skill whether financial and emotional investment to reduce risk and enhance rewards.